Espectrometria de Massa
|
Chemistry and Biochemistry Center |
|
Faculdade de Ciências da Universidade de Lisboa |
|
Rede Nacional de Espectrometria de Massa |
|
NÓ FCUL (RNEM) |
Tutorial de Espectrometria de massa em Português (Disponível brevemente)
Biochemistry/Biological Studies
- Interaction of organometallic complexes and carbohydrate derivatives with biomolecules (model proteins);
- Characterization of plant extracts; flavonoid and/or antioxidant compounds identification; correlation with antioxidant properties.
- Characterization of flavonoid metabolites in present in plasma; structure/antioxidant activity relationships.
- Metal ion quelation by flavonoids.
- Non-enzymatic glycation model reactions and the identification of intermediates and products formed; structure/activity studies.
Fundamental Studies: Theoretical methodologies, Gas Phase Energetics, Structure and Reactivity
- Application of theoretical calculations in mass spectrometry problems.
- Gas phase acidity of flavonoids.
- Metal afinity of flavonoids using the kinetic method.
- Gas phase acidity of substituted phenols.
- Proton afinities of terpenes.
Mass Spectrometry applications in Art Conservation Science
- Molecular studies on the ageing of oil paints formulated 1890-1940
Environmental Problems
- Development of low cost analytical methodologies for the photocatalityc degradation of organic pollutants in complex matrixes; characterization of the pollutants/intermediaries/degradation products.
- Development of separation, identification and characterization of micropollutants in complex matrixes; e.g. estuary waters, aquatic plants, sediments.
- Characterization of azides and study of their interaction with metallic ions.
Forensic Science
Collaborations
- Carbohydrate Chemistry Group (CQB)
- Organometallic and Bioorganometallic Chemistry Group (CCMM)
- Free Radicals, Health and Nutrition Group(CQB)
- Separation Science and Technology(CQB)
- Adsorption and Adsorbent Materials(CQB)
- Doctor João Paulo Leal, Unidade de Ciências Químicas e Radiofarmacêuticas, Instituto Tecnológico e Nuclear
- Doctor Jaap Boon, FOM Institute AMOLF, Amsterdam, Netherlands
- Doctor Magda Clayes, Bio-organic mass spectrometry, University of Antwerp, Belgium
- Doctor João Aires de Sousa, REQUIMTE, Departamento de Química, Faculdade de Ciências e Tecnologia da Universidade Nova de Lisboa
- Polícia Judiciária, Laboratório de Polícia Científica
- Doctor Cristina Cruz,Center for Environmental Biology, Faculdade de Ciências da Universidade de Lisboa
Projects
- Portuguese Mass Spectrometry Network - REDE/1501/REM/2005 (Fundação para a Ciência e a Tecnologia)
- RACHIs - Reduction on the Absorption of Cholesterol by Herbal Infusions (Functional Foods) - PTDC/QUI-BIQ/113477/2009 (Fundação para a Ciência e a Tecnologia)
- (Hiper)acumulação de Arsénico e outros Elementos por Plantas adaptadas a sítios contaminados por actividade Mineira e Metalúrgica. Especiação, Identificação de mecanismos de Acumulação e Desintoxicação e Aplicações em Bioremediação (HYPERAS). - PTDC/AMB/65462/2006 (Fundação para a Ciência e a Tecnologia)